The same but different: a comparison of Staphylococcus aureus bloodstream infections in metropolitan and non-metropolitan hospitals (2010-2020)

Bennett, N; Malloy, MJ; Atkins, SE; Gonelli, S; Worth, LJ

Author(s): Bennett, N; Malloy, MJ; Atkins, SE; Gonelli, S; Worth, LJ;
Details: Publication Year 2023-01,Volume 53,Issue #1,Page 89-94
Journal Title: Internal Medicine Journal
Publication Type: Research article
Abstract: BACKGROUND: Variation of infection rates between hospitals must be identified; differences may highlight opportunities for quality improvement in healthcare delivery to specific hospitals groups. AIMS: To analyse burden, time trends and risks of healthcare-associated (HA) Staphylococcus aureus bloodstream infections (SABSI) in patients admitted to Victorian metropolitan and non-metropolitan public acute care hospitals. METHODS: SABSI surveillance data submitted between 1 July 2010 and 30 June 2020 by all 118 Victorian public acute care hospitals were analysed. Aligned with the Australian Statistical Geography Standard Remoteness Structure, these hospitals were classified as metropolitan (major cities) or non-metropolitan (inner regional, outer regional, remote or very remote). RESULTS: Most SABSI were community associated: 66.9% and 75.0% of metropolitan (n = 9441) and non-metropolitan (n = 2756) hospital SABSI respectively. The overall HA-SABSI rate was statistically higher in metropolitan hospitals (1.13 per 10 000 occupied bed days (OBD)) compared with non-metropolitan hospitals (0.82 per 10 000 OBD; P < 0.001). In metropolitan and non-metropolitan hospitals, there was a statistically significant decline in the overall HA-SABSI rate (incidence rate ratio = 0.96; 95% confidence interval: 0.95-0.97; P < 0.001; and incidence rate ratio = 0.98; 95% confidence interval: 0.97-1.00; P = 0.044, respectively). In metropolitan and non-metropolitan hospitals, HA-SABSI were frequently associated with central venous (52.8%) and peripheral intravenous (62.2%) catheter use respectively. CONCLUSION: To reduce risks for SABSI and improve patient outcomes, hospital infection prevention and control programmes should be tailored according to local epidemiology. In common geographic locations, networking of hospitals should be considered as a means of strengthening delivery of these programmes.
Publisher: Wiley
Keywords: Humans; Australia/epidemiology; *Bacteremia/epidemiology; *Cross Infection/epidemiology; Hospitals, Public; *Staphylococcal Infections/epidemiology; Staphylococcus aureus; Staphylococcus aureus bloodstream infection; acute care hospital; surveillance
Department(s): Infectious Diseases; Infectious Diseases
PubMed ID: 34549859
Publisher's Version: https://doi.org/10.1111/imj.15538
Open Access at Publisher's Site: https://doi.org/10.1111/imj.15538
Terms of Use/Rights Notice: Refer to copyright notice on published article.

Creation Date: 2023-04-13 02:16:56

Last Modified: 2023-04-13 04:32:06